Table 2 Summary of the studies which included N100 component
From: Event-related potential studies of post-traumatic stress disorder: a critical review and synthesis
| Study | Subjects | Paradigm | Results |
|---|---|---|---|
| [31] |
12 combat PTSD veterans 6 normal controls | Four tones intensity paradigm | No difference in N1 amplitude |
| [17] |
20 Israeli combat veterans with PTSD 20 without PTSD |
Visual oddball, trauma related non-related neutral stimuli |
Combat-related pictures elicited enhanced N1 amplitude in PTSD group. Prolonged N1 latencies and reaction times to target stimuli in PTSD patients. |
| [56] |
16 medicated, 9 un-medicated PTSD 10 healthy veterans | Auditory three-tone oddball | Longer N100 latencies in un-medicated PTSD patients compared to the medicated PTSD and healthy controls. |
| [51] | 11 prisoners of war | Checkerboard reversal | Larger N75 amplitudes |
| [39] |
11 PTSD survivors of a ship fire 9 psychiatric controls from the same ship | Auditory word and non-word oddball |
Increased N1 latency to standard tones; Larger amplitude to emotionally meaningful words. |
| [25] |
13 females with sexual assault PTSD 16 healthy controls | Auditory oddball | No difference in N100 amplitude and latency |
| [28] |
17 civil PTSD 17 healthy controls | Auditory oddball | No difference in N100 amplitude or latency |
| [30] | 36 civil PTSD 20 healthy 10 depressed 8 alcoholics | 2000-Hz tone presented in increasing intensities | Increased N100 amplitudes |
| [38] |
15 civil PTSD 15 controls | Visual presentation of angry alternating with neutral faces |
Larger N110 to the angry compared to the neutral faces in the control group. Smaller and later N100 in PTSD subjects. |
| [35] |
10 civil PTSD 10 controls | Auditory oddball | Larger N100 amplitude |
| [42] | 19 PTSD 99 Alcohol dependence 16 personality disorder 25 anxiety or mood disorder | Visual presentation of happy, sad, and neutral faces | Larger N1 amplitudes to sad stimuli in frontotemporal leads in PTSD patients. |
| [57] |
16 civil PTSD 16 schizophrenia 16 control subjects | Auditory Oddball | No difference in N1 amplitude and latency |
| [36] |
14 PTSD [mixed etiologies] 12 controls | Auditory Oddball | No difference in N100 amplitude |